DEPARTMENT OF Cardiology

• Department:Cardiology
• Gender:Female
• Title:Director, Heart Center, Peking University People’s Hospital

Professional Highlights

2015-present  Director of Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction
2013-present  Member, Special Committee in Cardiovascular Disease, Chinese Medical Association
2013- present Member of editorial board, Chinese Journal of Cardiology
2013-present  Vice Chairman, Committee of Experts in the National Licensed Doctor Qualified Examination, National Medical Examination Center
2013-present  Vice Editor, Textbook of Cardiovascular Medicine for Standardized Resident Training, National Health and Family Planning Commission
2012-2015 Member of editorial board, Chinese Preventive Medical Journal
2011-2014 Chairman, Committee of Experts in Cardiologist Examination, National Medical Examination Center
2011-2016 Vice Chairman, Special Committee in Cardiovascular and Cerebrovascular Disease, Chinese Society of Gerontology
2010-2013 Vice Chairman, Society of Internal Medicine, Beijing Branch of Chinese Medical Association
2010-2013 Vice Chairman, Society of Internal Medicine, Beijing Medical Association
2010-present  Vice chairman, Special Committee in Cardiovascular Disease, Association of Medical Exchanges across the Taiwan Straits

Interests

Coronary artery disease, Dyslipidemia, Hypertension, Syncope, heart failure.

Research & Publications

1. Zhang F1, Li S2, Song J2, Liu J2, Cui Y2, Chen H3. Angiotensin-(1-7) regulates angiotensin II-induced matrix metalloproteinase-8 in vascular smooth muscle cells. Atherosclerosis. 2017. pii: S0021-9150(17)30064-3.
2. Cao CF#, Li SF#, Chen H*通讯作者, Song JX. Predictors and in-hospital prognosis of recurrent acute myocardial infarction. J Geriatr Cardiol. 2016; 13(10):836-839.
3. Song JX#, Zhu L#, Lee CY, Ren H, Cao CF, Chen H*通讯作者. Total ischemic time and outcomes for patients with ST-elevation myocardial infarction: does time of admission make a difference? J Geriatr Cardiol. 2016; 13(8):658-664.
4. Jin WY#, Zhao XJ, Chen H*通讯作者. Decreased diagnostic accuracy of multislice coronary computed tomographic angiography in women with atypical angina symptoms. Chin Med J (Engl). 2016; 129(18):2191-2198.
5. Zhang J#, Li SF, Chen H*通讯作者, Song JX. MiR-106b-5p inhibits tumor necrosis factor-α-induced apoptosis by targeting phosphatase and tensin homolog deleted on chromosome 10 in vascular endothelial cells. Chin Med J (Engl). 2016; 129(12):1406-1412.
6. Wang Z#, Cao C#, Guo C, Chen G, Chen H*通讯作者, Zheng X*. Socioeconomic inequities and cardiovascular disease-related disability in China: A population-based study. Medicine (Baltimore). 2016; 95(32):e4409.
7. Li S#, Chen H*通讯作者, Song J, Lee C, Geng Q. Avoiding heparin inhibition in circulating MicroRNAs amplification. Int J Cardiol. 2016; 207:92-93.
8. Zhang F#, Liu J, Li SF, Song JX, Ren JY, Chen H*陈红，通讯作者. Angiotensin-(1-7): new perspectives in atherosclerosis treatment. J Geriatr Cardiol. 2015; 12(6):676-82.
9. Li J#, Chen H*陈红，通讯作者, Ren J, Song J, Zhang F, Zhang J, Lee C, Li S, Geng Q, Cao C, Xu N. Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina. BMC Med Genomics. 2015; 8:1-14.
10. Gao Y#, Song J#, Chen H*陈红，通讯作者, Cao C, Lee C. TRPV1 activation is involved in the cardioprotection of remote limb ischemic postconditioning in ischemia-reperfusion injury rats. Biochem Biophys Res Commun. 2015;463(4):1034-1039.
11. Li S#, Ren J, Xu N, Zhang J, Geng Q, Cao C, Lee C, Song J, Li J, Chen H*陈红，通讯作者. MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. J Mol Cell Cardiol. 2014; 75:49-57.
12. Li S#, Chen H*陈红，通讯作者, Ren J, Geng Q, Song J, Lee C, Cao C, Zhang J, Xu N. MicroRNA-223 inhibits tissue factor expression in vascular endothelial cells. Atherosclerosis. 2014; 237: 514-520.
13. Geng Q#,  Ren JY,  Song JX,  Li SF, Chen H*陈红，通讯作者. Meta-analysis of the effect of statins on renal function. Am J Cardiol. 2014; 114(4): 562-570.
14. Zhang J #,  Ren JY,  Chen H*陈红，通讯作者,  Geng Q. Inflammation induced-endothelial cells release angiogenesis associated-microRNAscirculation by microparticles. Chin Med J. 2014; 127(12):2212-2217.
15. Li S#, An YZ, Ren JY, Zhu FX, Chen H*陈红，通讯作者. Myocardial injury after surgery is a risk factor for weaning failure from mechanical ventilation in critical patients undergoing major abdominal surgery. PLoS One. 2014; 9(11):e113410.
16. Ren JY#, Zhang J#, Xu N, Han GP, Geng Q, Song JX, Li SF, Zhao JQ, Chen H*陈红，通讯作者. Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. PLoS One. 2013; 8(12): e80738.
17. Cao CF#, Ren JY, Zhou XH, Li SF, Chen H*陈红，通讯作者. Twenty-year trends in major cardiovascular risk factors in hospitalized patients with acute myocardial infarction in Beijing. Chin Med J. 2013; 126(22): 4210-4215.
18. Zhang F#, Ren JY, Chan K, Chen H*陈红，通讯作者. Angiotensin-(1-7) regulates angiotensin II-induced VCAM-1 expression on vascular endothelial cells. Biochem Biophys Res Commun. 2013; 430(2): 642-646.
19. Geng Q#, Ren JY, Chen H*,陈红，通讯作者, Lee C, Liang WQ. Adverse events of statin-fenofibric acid versus statin monotherapy: a Meta-analysis of randomized controlled trials. Curr Med Res Opin. 2013; 29(3): 181-188.
20. Geng Q#, Ren JY, Chen H*陈红，通讯作者, Lee C, Liang WQ. Adverse events following statin-fenofibrate therapy versus statin alone: a Meta-analysis of randomized controlled trials. Clin Exp Pharmacol Physiol. 2013; 40(3):219-226.
21. Han GP#, Ren JY, Qin L, Song JX, Wang L, Chen H*陈红，通讯作者. High density lipoprotein suppresses lipoprotein associated phospholipase A2 in human monocytes-derived macrophages through peroxisome proliferator-activated receptor-γ pathway. Chin Med J. 2012; 125(24): 4474-4480.
22. Liu CF#, Qin L#, Ren JY, Chen H*陈红，通讯作者, Wang WM, Liu J, Song JX, Li LJ. Elevated plasma lipoprotein-associated phospholipase A2 activity is associated with plaque rupture in patients with coronary artery disease. Chin Med J. 2011; 124(16):2469-2473.
23. Ren JY#, Song JX, Lu MY, Chen H*陈红，通讯作者. Cardioprotection by ischemic postconditioning is lost in isolated perfused heart from diabetic rats: Involvement of transient receptor potential vanilloid 1, calcitonin gene-related peptide and substance P. Regul Pept. 2011; 169(1-3): 49-57.
24. Song JX#, Ren JY, Chen H*陈红，通讯作者. Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. J Cardiovasc Pharmacol. 2011; 57(2): 213-222.
25. Jiang G#, Chen H*通讯作者, Wang S, Zhou Q, Li X, Chen K, Sui X. Learning curves and long-term outcome of simulation-based thoracentesis training for medical students. BMC Medical Education. 2011;11(6):39-45.
26. Ren JY#, Jin WY#, Chen H*陈红，通讯作者. oxHDL decreases the expression of CD36 on human macrophages through PPARgamma and p38 MAP kinase dependent mechanisms. Mol Cell Biochem. 2010; 342(1-2):171-181.
27. Chen H*通讯作者, Ren JY, Xing Y, Zhang WL, Liu X, Wu P, Wang RJ, Luo Y. Short-term withdrawal of simvastatin induces endothelial dysfunction in patients with coronary artery disease: A dose-response effect dependent on endothelial nitric oxide synthase. Int J Cardiol. 2009; 131(3):313-320.
28. Qiao ZG#, Ren JY#, Chen H*通讯作者. Simvastatin reduces expression and activity of lipoprotein-associated phospholipase A(2) in the aorta of hypercholesterolaemic atherosclerotic rabbits. J Int Med Res. 2009; 37(4): 1029-1037.
29. Chen H*通讯作者, Xing Y, Liu R. Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells. Chin Med J(Engl). 2001; 114(11):1123-1127.
30. Chen H#, Ikeda U*, Shimpo M, Ikeda M, Minota S, Shimada K. Fluvastatin upregulates inducible nitric oxide synthase expression in cytokine-stimulated rat vascular smooth muscle cells. Hypertension. 2000; 36(6):923-928.
31. Chen H#, Ikeda U*, Shimpo M, Maeda Y, Shibuya M, Ozawa K, Shimada K.. Inhibition of vascular endothelial growth factor activity by transfection with the soluble FLT-1 gene. J Cardiovasc Pharmacol. 2000; 36(4):498-502.
32. Chen H#, Ikeda U*, Shimpo M, Shimada K. Direct effects of statins on cells primarily involved in atherosclerosis. Hypertens Res. 2000; 23(2):187-192. 

Others

Awards
2016 The special prize of Baosteel Outstanding Teacher Award
2015 The title of the 7th “Young and Middle-aged Experts for National Health and Family Planning”
2014 Scholar Awards of the 8th WuXi Pharma Tech Life Science and Chemistry Research Awards—“Basic and clinical research of atherosclerosis”
2014 The 1st prize of “National Teaching Achievement Award of Higher Education”
2013 The 3rd Prize of Science and Technology Award of Chinese Preventive Medicine Association--“The study on the underlying mechanism and clinical intervention of statins in preventing and treating atherosclerosis”
2013 The title of “State Council Expert for Special Allowance”
2011 The Prize of Wu Jieping Medical Research and Paul Johnson Pharmaceutical Research Award
2011 The 3rd Prize of Science and Technology Award of Chinese Medical Association--“Clinical and basic research on statins in preventing atherosclerosis”
2011 The 3rd Prize of Huaxia Medical Science and Technology Award—“Clinical and basic research on statins in preventing atherosclerosis”
2011 The 3rd Prize of Beijing Science and Technology Award--“Clinical and basic research on statins in preventing atherosclerosis”
2010 The 3rd Prize of Beijing Science and Technology Award--“Clinical and basic research on statins in preventing atherosclerosis”
2010 The award of Beijing Famous Teacher Award of Higher Education
2009 The 1st Prize of “National Teaching Achievement Award of Higher Education”
2009 The title of “Beijing Excellent Teacher”
2008 The 1st prize of “Beijing Teaching Achievement Award of Higher Education”

 

Publications

2015 Clinical Diagnosis (3rd Edition), People’s Medical Publishing House.
2015 Basics of Diagnosis (4 th Edition), Peking University Medical Press
2014 Operational Guidelines of Clinical Skills for Chinese Medical Students (2nd Edition), People’s Medical Publishing House.
2013 Diagnosis and Treatment of Dyslipidemia (2nd Edition), People’s Military Medical Press

 

Translation

2016 Harrison’s Manual of Medicine (18th Edition), Peking University Medical Press.
2012 Clinical Lipidology, A Companion to Braunwalds Heart Disease, Peking University Medical Press.